LITERATURE REVIEW: POLA KEPEKAAN SALMONELLA TYPHI TERHADAP ANTIBIOTIK PADA PASIEN DEMAM TIFOID ANAK

Novatalia Batosamma, Noor Muthmainah, Rahmiati Rahmiati, Dewi Indah Noviana Pratiwi, Lisda Hayatie

Abstract


Typhoid fever is one of the major health problems in the world, especially in developing countries. The highest typhoid fever morbidity is found in children, especially school age children. Patients often self-medicate with antibiotics, the main antibiotic of choice for typhoid fever in Indonesia is chloramphenicol but in some places resistance to the chloramphenicol group has been reported. When writing, related literature is examined using search results from Google Scholar and PubMed - MEDLINE, two medical journal databases. articles from 2012 to 2019 that were published in English. This literature study contained a total of 8 papers. The article published in this literature review shows the presence of resistant isolates in the Salmonella thypi antibiotic susceptibility test in the main therapy given. In some cases, they have resistance to ceftriaxone, cefuroxime, amoxicillin, ampicillin, ciprofloxacin, augmentin, fluoroquinolones, azithromycin, and nalidixic acid. Some of the drugs mentioned as sensitive to S. Typhi are Cefixime, ceftriaxone, chloramphenicol, ofloxacin, cefepime, quinolones, and third generation cephalosporins.

 


Keywords


antibiotic, typhoid fever, children, Salmonella typhi

Full Text:

PDF

References


Sudoyo A W, Setyohadi B, Alwi I dkk. Buku Ajar Ilmu Penyakit Dalam. Jilid III Edisi V. Jakarta: Interna Publishing Pusat Penerbitan Ilmu Penyakit Dalam. 2009 ; 2773-2779.

Centers for Disease Control and Prevenion. Morbidity and Mortality Weekly Report. 2008;83(6): 49-60.

Chau TT, Campbell JI, Galindo CM, Van Minh Hoang N, Diep TS, Nga TT, et al. Antimicrobial Drug Resistance of Salmonella enterica serovar typhi in Asia and Molecular Mechanism of Reduced Susceptibility to The Fluoroquinolones. Antimicrob Agents Chemother. 2007 Dec. 51(12):4315-23.

World Health Organization. Bulletin of the World Health Organization 2008;86 (5):321–46.

Badan Litbang Kesehatan. Riset Keseha-tan Dasar 2007. Jakarta; 2008. Diundu di: https://www.k4health.org/sites/de fault/files/laporanNasionalRiskes das2007pdf. (Diakses 20 Mei 2015).

Yogita SP, Hendrayana MA, Sukrama IDM. Pola kepekaan bakteri Salmonella typhi Terisolasi Dari Darah Terhadap Siprofloksasin dan Seftriakson di RSUP Sanglah periode Januari 2015-Maret 2017. E-Jurnal Medika. DOAJ. Bali. 2018. 7(12):1-6.

Adabara NU, Ezugwu BU, Momojimoh A, Madzu A, Hashiimu Z, Damisa D. The prevalence and antibiotic susceptibility pattern of Salmonella typhi among patients attending a military hospital in Minna, Nigeria. Advances in preventive medicine. 2012 Sep 28;2012.

Dahiya S, Malik R, Sharma P, Sashi A, Lodha R, Kabra SK, Sood S, Das BK, Walia K, Ohri VC, Kapil A. Current antibiotic use in the treatment of enteric fever in children. The Indian Journal of Medical Research. 2019 Feb;149(2):263.

Emary K, Moore CE, Chanpheaktra N, An KP, Chheng K, Sona S, Duy PT, Nga TV, Wuthiekanun V, Amornchai P, Kumar V. Enteric fever in Cambodian children is dominated by multidrug-resistant H58 Salmonella enterica serovar Typhi with intermediate susceptibility to ciprofloxacin. Transactions of the Royal Society of Tropical Medicine and Hygiene. 2012 Dec 1;106(12):718-24.

Sauteur PM, Stevens MJ, Paioni P, Wüthrich D, Egli A, Stephan R, Berger C, Bloemberg GV. Siblings with typhoid fever: An investigation of intrafamilial transmission, clonality, and antibiotic susceptibility. Travel medicine and infectious disease. 2020 Mar 1;34:101498.

Limpitikul W, Henpraserttae N, Saksawad R, Laoprasopwattana

K. Typhoid outbreak in Songkhla, Thailand 2009–2011: clinical outcomes, susceptibility patterns, and reliability of serology tests. PLoS One. 2014 Nov 6;9(11):111768.

Khatun H, Islam SB, Naila NN, Islam SA, Nahar B, Alam NH, Ahmed T. Clinical profile, antibiotic susceptibility pattern of bacterial isolates and factors associated with complications in culture‐proven typhoid patients admitted to an urban hospital in Bangladesh. Tropical Medicine & International Health. 2018 Apr;23(4):359-66.

Patel SR, Bharti S, PRataP CB, Nath G. Drug resistance pattern in the recent isolates of Salmonella Typhi with special reference to cephalosporins and azithromycin in the Gangetic plain. Journal of clinical and diagnostic research: JCDR. 2017 Jun;11(6):DM01.

World Health Organization. Bulletin of the World Health Organization 2008;86 (5):321–46.

Suswati I, Juniarti A. Sensitivitas Salmonella typhi terhadap Kloramfenikol dan Seftriakson di RSUD Dr. Soetomo Surabaya dan di RSUD Dr. Saiful Anwar Malang Tahun 2008-2009.




DOI: https://doi.org/10.20527/ht.v6i3.11476

Refbacks

  • There are currently no refbacks.


Copyright (c) 2023 Homeostasis

Creative Commons License
Homeostasis is licensed under a Creative Commons Attribution 4.0 International License

Program Studi Kedokteran Program Sarjana
Fakultas Kedokteran Universitas Lambung Mangkurat
Jalan Veteran No.128 Banjarmasin
Phone: +62-878-1546-0096
email : [email protected]