POTENSI BUAH NANGKA (Artocarpus heterophyllus L) SEBAGAI ANTIDIABETES IN VITRO

Khairina Khairina; Eko Suhartono; Agung Biworo

doi:10.20527/jbk.v11i2.142

POTENSI BUAH NANGKA (Artocarpus heterophyllus L) SEBAGAI ANTIDIABETES IN VITRO

Khairina Khairina, Eko Suhartono, Agung Biworo

Abstract

Artocarpus species have been used by traditional medicine of Indonesian. It can be useful as anti-bacterial, anti-diabetic, anti-inflammatory, antioxidant and anti-helmintics. The present study was aimed to test the inhibitory glycated hemoglobin potency of aqueous extract of Jackfuit. This study is a quasi experimental research with non randomized method post test-only group design, which using a model reaction of two groups : extract jackfruit as the test group and glikazid as the control group, with each concentration of 10%, 20%, 30%. Potential inhibitor of glycated hemoglobin jackfruit as determining the amount of IC50. From this research got IC50 of jackfruit extracts is 56,43% (r=0,999) whereas for glikazid of 17.268 (r = 0.989). The value of r indicates a positive relationship between the concentration and the inhibitor glycated hemoglobin potential. These results indicate that the extract of Jackfruit has potential as an inhibitor glycated hemoglobin.

Keywords: glycated hemoglobin, jackfruit, Artocarpus heterophllus L, glikazid.

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DOI: http://dx.doi.org/10.20527/jbk.v11i2.142