Eficacy the Use of Combined Goji Berry Cream for Skin Rejuvination and Post-Inflammatory Hyperpigmentation: Two Case Reports

Abstract

The antioxidant content in Goji Berries is known to prevent various signaling pathways in inflammation. Recent research is beginning to look at the potential of Goji berries in topical preparations for skin rejuvenation as well as their potential to reduce post-inflammatory hyperpigmentation. Two cases of post-inflammatory hyperpigmentation in a 29-year-old man and a 26-year-old woman were reported. The patients were given Goji berry combination cream therapy once daily for 4 weeks. The efficacy of therapy was assessed based on comparative evaluation of clinical conditions, skin analyzer examination, melanin index and erythema index examination with a mexameter, and Transepidermal Water Loss (TEWL) examination with a tewameter. After therapy, there was a decrease in the number of pores, wrinkles, pigmentation, melanin index value, erythema index, and improvement in TEWL in both patients. The use of a combination cream of Goji berry, niacinamide, vitamin E, ubiquinone, ceramide, and hyaluonic acid for skin rejuvenation and improving post-inflammatory hyperpigmentation due to acne vulgaris can be considered as an effective, comfortable, and safe therapeutic modality for patients.