THE EFFECT OF CALCIUM HYDROXIDE PARTICLE SIZE ON DENTIN TUBULI HARDNESS

Atia Nurul Sidiqa, Pahargyan Arya Rajasa, Hartanto Endrowahyudi, Myrna Nurlatifah Zakaria

Abstract


Background: Calcium hydroxide (Ca(OH)2) is an effective root canal treatment, with calcium and hydroxyl ions effectively released on day 7. However, prolonged use can diminish dentinal tubule hardness and dissolve the hydroxyapatite crystals within them. Nanoparticle Ca(OH)2 demonstrated superior antimicrobial activity compared to conventional Ca(OH)2 because of its deeper penetration into the dentinal tubules.. Purpose: This study aimed to evaluate the effect of particle size on dentinal tubule hardness. Methods: True experiment with fifteen premolars with one root canal, no caries, and apical closure were divided into three treatment groups: conventional Ca(OH)2 (group 1, n=5), Ca(OH)2 nanoparticles (group 2, n=5), and untreated (control group), n=5. All samples were incubated for 7 days, and hardness was measured using a micro-Vickers hardness tester at 1/3 of the root canal. Kruskal-Wallis test followed by Mann-whitney post hoc analysis was used to compare the mean microvickers hardness values among different groups. The level of significance was set at p<0.05. Results: The results showed that there was significant difference between conventional Ca(OH)2 (73.00 ± 2.71) and Ca(OH)2 nanoparticles (67.40 ± 0.62) p=0.01 and the control group (70.68 ± 1.70; p>0.05) and Ca(OH)2 nanoparticles p=0.03. Conclusions: The use of Ca(OH)2 nanoparticles as an intracanal medicament for 7 days reduced dentin microhardness, whereas conventional Ca(OH)2 did not result in any change in microhardness. Particle size affects the hardness of dentinal tubules.

Keywords


Nanoparticle; Hardness; Medicament; Root Canal Treatment

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Rangareddy MS, Priya P. S, Karteek BS, Swetha C, Kumar BS, Waheed S, et al. A comparative evaluation of antimicrobial efficacy of various intracanal medicaments (Curcuma longa , honey, nitrofurantoin, and calcium hydroxide) on Enterococcus faecalis : an in vitro study. J Pharmacol Pharmacother. 2024 Apr 5;

Teja KV, Janani K, Srivastava KC, Shrivastava D, Natoli V, Di Blasio M, et al. Comparative evaluation of antimicrobial efficacy of different combinations of calcium hydroxide against Enterococcus faecalis. BMC Oral Health. 2023 Dec 1;23(1).

Ordinola-Zapata R, Noblett WC, Perez-Ron A, Ye Z, Vera J. Present status and future directions of intracanal medicaments. Vol. 55, International Endodontic Journal. John Wiley and Sons Inc; 2022. p. 613–36.

Sy K, Chevalier C, Maton M, Mokbel I, Mahieux S, Houcke I, et al. Therapeutic potential of chlorhexidine-loaded calcium hydroxide-based intracanal medications in endo-periodontal lesions: an ex vivo and in vitro study. Antibiotics. 2023 Sep 7;12(9):1416.

Karamifar K. Endodontic Periapical Lesion: An Overview on Etiology, Diagnosis and Current Treatment Modalities. Eur Endod J. 2020;

Purohit D, Shronika, Misra P, Jain G, Shukla P. Role of vehicles on antimicrobial efficacy of calcium hydroxide. Asian Journal of Oral Health and Allied Sciences. 2023 Dec 30;13:9.

Sidiqa AN, Zakaria MN, Artilia I, Dewi ZY, Cahyanto A. Evaluation of calcium ion release in calcium hydroxide prototype as intracanal medicament. Journal of Dentomaxillofacial Science. 2020 Aug 1;5(2):86.

Dalavai P, Nasreen F, Srinivasan R, Pramod J, Bhandary S, Penmatsa C. To evaluate and compare the compressive strength of root dentin exposed to calcium hydroxide, mixed with various vehicles for a period of 30 days – An in vitro study. Journal of Conservative Dentistry. 2021;24(6):563.

Sethi S, Gupta A, Kurian A, Abraham D, Chauhan P, Aneja K, et al. Effect of calcium hydroxide on fracture resistance and microhardness of dentin in human teeth: A systematic review. Endodontology. 2022;34(4):223.

Mohamed AA, Fayyad DM, El-Telbany M, Mohamed DAA. Antibacterial biofilm efficacy of calcium hydroxide loaded on Gum Arabic nanocarrier: an in-vitro study. BMC Oral Health. 2024 Feb 10;24(1):215.

Zakaria MN, Sidiqa AN, Artilia I, Cahyanto A. Synthesis and characterization of calcium hydroxide from Indonesian limestone as endodontic intracanal medicament. Key Eng Mater. 2018 Oct;782:268–72.

Sidiqa AN, Zakaria MN, Cahyanto A, Joni IM, Maskoen AM. Carbonation inhibitor by polyethylene glycol encapsulation of calcium hydroxide fine particles to improve antimicrobial and root canal penetration properties. Heliyon. 2023 Jul;9(7):e18005.

Marinho ACS, To TT, Darveau RP, Gomes BPFA. Detection and function of lipopolysaccharide and its purified lipid A after treatment with auxiliary chemical substances and calcium hydroxide dressings used in root canal treatment. Int Endod J. 2018 Oct;51(10):1118–29.

Sidiqa AN, Zakaria MN, Artilia I, Cahyanto A, Puti LN. Evaluasi Kadar pH Kalsium Hidroksida Hasil Sintesis Batu Kapur Alam Sebagai Alternatif Bahan Medikamen Intrakanal. In: Preparing Dentist Approach Of The Industrial Revolution 40. Bali: Universitas Mahasaraswati; 2019. p. 24–9.

Rahimi S, Ghasemi N, Jabbari G, Zaheri Z, Torabi Z, Darehchi N. Effect of different intracanal medicaments on the fracture resistance of the human root. Dent Res J (Isfahan). 2022;19(1):9.

Krastl G, Weiger R, Filippi A, Van Waes H, Ebeleseder K, Ree M, et al. Endodontic management of traumatized permanent teeth: a comprehensive review. Int Endod J. 2021 Aug 31;54(8):1221–45.

Komabayashi T, Nonomura G, Watanabe LG, Marshall GW, Marshall SJ. Dentin tubule numerical density variations below the CEJ. J Dent. 2008 Nov;36(11):953–8.

Yassen GH, Chu TMG, Eckert G, Platt JA. Effect of Medicaments Used in Endodontic Regeneration Technique on the Chemical Structure of Human Immature Radicular Dentin: An In Vitro Study. J Endod. 2013 Feb;39(2):269–73.

Naseri M, Eftekhar L, Gholami F, Atai M, Dianat O. The effect of calcium hydroxide and nano–calcium hydroxide on microhardness and superficial chemical structure of root canal dentin: an ex vivo study. J Endod. 2019 Sep;45(9):1148–54.

Hedgire DrA, Bhondwe DrS, Mahajan DrV, Daule DrR, Chechare DrS. The effects of short-term calcium hydroxide application on the strength of dentine. Scholars Journal of Dental Sciences. 2022 Jan 28;9(1):21–4.

Al‐Hiyasat AS, El‐Farraj HS, Alebrahim MA. The effect of calcium hydroxide on dentine composition and root fracture resistance of human teeth: An in vitro study. Eur J Oral Sci. 2021 Aug 20;129(4).




DOI: http://dx.doi.org/10.20527/dentino.v9i2.20404

DOI (PDF): http://dx.doi.org/10.20527/dentino.v9i2.20404.g10413

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