MANDIBULAR BONE QUALITY OF PANORAMIC RADIOGRAPHS IN HIV-INFECTED CHILDREN

Ria Noerianingsih Firman, Irna Sufiawati, Risti Saptarini Primarti, Aga Satria Nurrachman, Merry Annisa Damayanti

Abstract


Background: People living with HIV may have several pathologic conditions in its body and bone is one of the organs affected by HIV infection. HIV-infected patients have been associated frequently with osteoporosis and lower bone mineral density (BMD) which may lead to the increasing risk of bone fracture. This situation may become more complicated in children and young age as it will affect the long-term bone quality and development later in life until the peak BMD is reached. Objectives: The aim of this study was to measure the mandibular bone quality using the mandibular cortical index (MCI) and panoramic mandibular index (PMI) in panoramic radiographs of HIV-infected children. Method: This study used descriptive cross sectional research design which analyzed panoramic radiographs of HIV-infected children and measured its mandibular bone quality. Total 43 panoramic radiographs of HIV-infected children were observed and analyzed qualitatively using mandibular cortical index (MCI) and panoramic mandibular index (PMI) were used for the quantitave measurement, as it have been widely used for assesing mandibular bone quality in previous studies. Mandibular cortical index (MCI) has 3 categories of cortical bone quality: C1 (normal cortex), C2 (mildly to moderately eroded cortex), and C3 (severely eroded cortex), while the normal ratio of mental foramen-inferior border of mandible to mandibular cortical length in panoramic mandibuIar index is about 0.3. Result: Mandibular cortical index (MCI) of 43 HIV-infected children consist of 4 samples in C1, 38 in  C2, 1 in C3, while the panoramic mandibular index (PMI) of 43 HIV-infected children consist of 23 less than normal, 5 normal, 15 more than normal. Conclusions: The most number of mandibular cortical index (MCI) was C2 (mildly to moderately eroded cortex) and the most number of panoramic mandibular index (PMI) was less than normal of HIV-infected children.

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References


Stevens M, Nixon S. Research on rehabilitation interventions for adults living with HIV: a scoping review. Int J Rehabil Res. 2016;39:106–1116.

UNAIDS. AIDS by the numbers. UNAIDS; Published 2015 [cited 2016 Jul 21]. Available from: http://www.unaids.org/sites/default/files/media_asset/AIDS_by_the_numbers_2015_en.pdf.

Januraga PP, Reekie J, Mulyani T, Lestari BW, Iskandar S, Wisaksana R, et al. The cascade of HIV care among key populations in Indonesia : a prospective cohort study. Lancet HIV. 2018;5(10):e560–8.

Güerri-Fernández R, Villar-García J, Díez-Pérez A, Prieto-Alhambra D. HIV infection, bone metabolism, and fractures. Arq Bras Endocrinol Metabol. 2014;58(5):478–83.

Kruger MJ, Nell TA. Bone mineral density in people living with HIV : a narrative review of the literature. AIDS Res Ther. 2017;1–17.

Nittayananta W, Kanjanaprapas A, Arirachakaran P, Pangsomboon K, Sriplung H. Alveolar bone in human immunodeficiency virus infection : is it changed by long-term antiretroviral therapy ? Int Dent J. 2016;1–7.

Bunders MJ, Frinking O, Scherpbier HJ. Bone Mineral Density Increases in HIV-Infected Children Treated With Long- term Combination Antiretroviral Therapy Bone Mineral Density Increases in HIV-Infected Children Treated With Long-term Combination Antiretroviral Therapy. 2012;(October).

Mccomsey GA, Tebas P, Shane E, Yin MT, Overton ET, Huang JS, et al. Bone Disease in HIV Infection : A Practical Review and Recommendations for HIV Care Providers. Clin Infect Dis. 2010;51:937–46.

Eckard AR, Mora S. Bone Health in HIV-infected Children and Adolescents. Curr Opin HIV AIDS. 2017;11(3):294–300.

Brown TT, Ruppe MD, Kassner R, Kumar P, Kehoe T, Dobs AS, et. al. Reduced bone mineral density in human immunodeficiency virus-infected patients and its association with increased central adiposity and postload hyperglycemia. J Clin Endocrinol Metab. 2004.

Shiau S, Yin MT, Strehlau R, Patel F, Mbete N, Kuhn L, et al. Decreased bone turnover in HIV-infected children on antiretroviral therapy. Arch Osteoporos. 2018;13(1).

Saccomanno MF, Ammassari A. Bone disease in HIV infection. 2011;8(1):33–6.

Bajoria AA, Ml A, Kamath G, Babshet M, Patil P, Sukhija P. Evaluation of Radiomorphometric Indices in Panoramic Radiograph – A Screening Tool. Open Dent J. 2015;9(Suppl 2: M9):303–10.

Yalcin ED, Avcu N, Uysal S, Arslan U. Evaluation of Radiomorphometric Indices and Bone Findings on Panoramic Images in Patients with Scleroderma. Oral Surg Oral Med Oral Pathol Oral Radiol. 2018;

15.Tofangchiha M, Javadi A. Diagnosis of osteoporosis using cortex mandibular indices based on cortex thickness and morphology in comparison with visual assessment of the cortex. J Craniomax Res. 2017;4(2):345–51.

Kwon A, Huh K, Yi W, Lee S, Choi S, Heo M. Is the panoramic mandibular index useful for bone quality evaluation ? Imaging Sci Dent. 2017;47:87–92.

Hastar E, Yilmaz HH, Orhan H. Evaluation of Mental Index , Mandibular Cortical Index and Panoramic Mandibular Index on Dental Panoramic Radiographs in the Elderly. Eur J Dent. 2011;5:60–7.

Gulsahi A, Yuzugullu B, Imirzahoglu P, Genc Y. Assessment of panoramic radiomorphometric indices in Turkish patients of different age group, gender and dental status. Dentomaxillofacial Radiol. 2008;37:288–92.

Dagistan S, Bilge OM. Comparison of antegonial index , mental index , panoramic mandibular index and mandibular cortical index values in the panoramic radiographs of normal males and male patients with osteoporosis. Dentomaxillofacial Radiol. 2010;39:290–4.

Cervero M, Torres R, Agud JL, Alcázar V, Jusdado JJ, García-Lacalle C, et al. Prevalence of and risk factors for low bone mineral density in Spanish treated HIV-infected patients. PLoS One. 2018;13(4):1–18.

Donà D, Mozzo E, Luise D, Lundin R, Padoan A, Rampon O, et al. Impact of HIV-1 Infection and Antiretroviral Therapy on Bone Homeostasis and Mineral Density in Vertically Infected Patients. J Osteoporos. 2019;2019:1–7.

Kakar A, Kothakota SR, Bashyam S, Gogia A. Bone Mineral Density in HIV / AIDS – A Case Control Study with Review of Literature Abstract. J HIV Retrovir. 2019;5(1):1–8.

Vlot MC, Grijsen ML, Prins JM, de Jongh RT, de Jonge R, den Heijer M, et al. Effect of antiretroviral therapy on bone turnover and bone mineral density in men with primary HIV-1 infection. PLoS One. 2018;13(3):1–11.




DOI: http://dx.doi.org/10.20527/dentino.v5i1.8129

DOI (PDF): http://dx.doi.org/10.20527/dentino.v5i1.8129.g6025

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