PENURUNAN KADAR ASAM URAT DARAH AYAM JANTAN BROILLER HIPERURISEMIA OLEH FRAKSI PETROLEUM ETER DAUN KEPEL (Stelechocarpus burahol Hook.)
Abstract
Telah dilakukan penelitian mengenai penurunan kadar asam urat darah ayam jantan broiller hiperurisemia oleh fraksi petroleum eter daun kepel (Stelechocarpus burahol Hook.). Penelitian dilakukan menggunakan rancangan sederhana pola dua arah. Kontrol negatif diberi suspensi Na CMC 0,5% secara peroral 5 ml/kgBB. Kontrol positif diberi alopurinol secara peroral 10 mg/kgBB. Fraksi petroleum eter diberikan secara peroral dengan dosis 25, 50, 100, dan 150 mg/kgBB. Pengambilan sampel darah dilakukan pada jam ke-0, 1, 2, 4, dan 8 setelah perlakuan.
Hasil perlakuan melalui perhitungan AUC0-8 menunjukkan bahwa perlakuan fraksi petroleum eter dengan dosis 25, 50, 100, dan 150 mg/kgBB menurunkan kadar asam urat darah ayam berturut-turut 21,56; 17,62; 31,46; dan 24,59% dibandingkan dengan kontrol negatifnya, signifikan pada taraf nyata P<0.05.
Kata Kunci : Kepel, hiperurisemia, fraksi, asam urat, alopurinol.
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PDFDOI: http://dx.doi.org/10.20527/jstk.v2i1.2014
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We are pleased to inform you that the result of our application for journal accreditation has been finalized through the Arjuna system. Based on the assessment result, Jurnal Ilmiah Berkala Sains dan Terapan Kimia has now been officially accredited by Ministry of Research, Technology, and Higher Education of Republic of Indonesia with a predicate of SINTA 3. The official letter of the accreditation result is available through this link.
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Alamat Redaksi:
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PROGRAM STUDI KIMIA
Kampus Fakultas Matematika dan Pengetahuan Alam, Gedung I,
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